An improved secretion signal enhances the secretion of model proteins from Pichia pastoris

Abstract Background Proteins can be secreted from a host organism with the aid of N-terminal secretion signals. The budding yeast Pichia pastoris (Komagataella sp.) is widely employed to secrete proteins of academic and industrial interest. For this yeast, the most commonly used secretion signal is...

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Bibliographic Details
Main Authors: Juan J. Barrero, Jason C. Casler, Francisco Valero, Pau Ferrer, Benjamin S. Glick
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-018-1009-5