EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAMhigh/CD44+ colorectal cancer stem cells

A small subpopulation of colorectal cancer stem cells (CSCs) possess the ability to self-renew and the capacity to initiate the original tumor. EpCAMhigh/CD44+ cells are regarded as CSCs in colorectal cancer. The present study was undertaken to investigate the significance of EpCAM in the in vitro p...

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Bibliographic Details
Main Authors: Qi Yanmei, Zhou Fengqiang, Geng Zhen, Ding Baozhong, Liu Lei
Format: Article
Language:English
Published: De Gruyter 2022-07-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2021-0301