Inferring reaction network structure from single-cell, multiplex data, using toric systems theory.
The goal of many single-cell studies on eukaryotic cells is to gain insight into the biochemical reactions that control cell fate and state. In this paper we introduce the concept of Effective Stoichiometric Spaces (ESS) to guide the reconstruction of biochemical networks from multiplexed, fixed tim...
| 主要な著者: | , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Public Library of Science (PLoS)
2019-12-01
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| シリーズ: | PLoS Computational Biology |
| オンライン･アクセス: | https://doi.org/10.1371/journal.pcbi.1007311 |