Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells

Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells

Recently, biodegradable polyelectrolyte multilayer capsules (PMC) have been proposed for anticancer drug delivery. In many cases, microencapsulation allows to concentrate the substance locally and prolong its flow to the cells. To reduce systemic toxicity when delivering highly toxic drugs, such as...

Full description

Bibliographic Details
Main Authors: Anastasia Gileva, Daria Trushina, Anne Yagolovich, Marine Gasparian, Leyli Kurbanova, Ivan Smirnov, Sergey Burov, Elena Markvicheva
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nanomaterials
Subjects:
polyelectrolyte multilayer capsules
antitumor protein DR5-B
targeted drug delivery
codelivery system
tumor spheroids
HCT-116 cells
Online Access:https://www.mdpi.com/2079-4991/13/5/902

Internet

https://www.mdpi.com/2079-4991/13/5/902

Similar Items