L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

Abstract Dopamine plays important roles in cognitive function and inflammation and therefore is involved in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD). Drugs that increase or maintain dopamine levels in the brain could be a therapeutic strategy for AD. Ho...

Full description

Bibliographic Details
Main Authors: Hyun-ju Lee, JinHan Nam, Jeong-Woo Hwang, Jin-Hee Park, Yoo Joo Jeong, Ji-Yeong Jang, Su-Jeong Kim, A-Ran Jo, Hyang-Sook Hoe
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Molecular Brain
Subjects:
L-DOPA
Aβ
Tau
Neuroinflammation
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s13041-024-01092-8

Internet

https://doi.org/10.1186/s13041-024-01092-8

Similar Items