Facile detection of mechanical forces across proteins in cells with STReTCh
Summary: Numerous proteins experience and respond to mechanical forces as an integral part of their cellular functions, but measuring these forces remains a practical challenge. Here, we present a compact, 11-kDa molecular tension sensor termed STReTCh (sensing tension by reactive tag characterizati...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
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Series: | Cell Reports: Methods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667237522001552 |