Facile detection of mechanical forces across proteins in cells with STReTCh

Summary: Numerous proteins experience and respond to mechanical forces as an integral part of their cellular functions, but measuring these forces remains a practical challenge. Here, we present a compact, 11-kDa molecular tension sensor termed STReTCh (sensing tension by reactive tag characterizati...

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Bibliographic Details
Main Authors: Brian L. Zhong, Vipul T. Vachharajani, Alexander R. Dunn
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Cell Reports: Methods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237522001552