A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke

Abstract Observational studies have shown an association between post-traumatic stress disorder (PTSD) and ischemic stroke (IS) but given the susceptibility to confounding it is unclear if these associations represent causal effects. Mendelian randomization (MR) facilitates causal inference that is...

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Bibliographic Details
Main Authors: Opeyemi Soremekun, Clarisse Musanabaganwa, Annette Uwineza, Maddalena Ardissino, Skanda Rajasundaram, Agaz H. Wani, Stefan Jansen, Jean Mutabaruka, Eugene Rutembesa, Chisom Soremekun, Cisse Cheickna, Mamadou Wele, Joseph Mugisha, Oyekanmi Nash, Eugene Kinyanda, Dorothea Nitsch, Myriam Fornage, Tinashe Chikowore, Dipender Gill, Derek E. Wildman, Leon Mutesa, Monica Uddin, Segun Fatumo
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02542-y