Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice

Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI). We recently established an ameloblast-specific (AmelX-iCre) Stim1 conditional deletion mouse model to inve...

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Bibliographic Details
Main Authors: Raed Said, Helyasadat Mortazavi, David Cooper, Katie Ovens, Ian McQuillan, Silvana Papagerakis, Petros Papagerakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Physiology
Subjects:
enamel
calcium
ameloblast
amelogenesis
stromal interacting molecule 1 (STIM1)
store operated Ca 2+ entry
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1100714/full

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https://www.frontiersin.org/articles/10.3389/fphys.2023.1100714/full

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