Bulged and Canonical G-Quadruplex Conformations Determine NDPK Binding Specificity
Guanine-rich DNA strands can adopt tertiary structures known as G-quadruplexes (G4s) that form when Hoogsteen base-paired guanines assemble as planar stacks, stabilized by a central cation like K<sup>+</sup>. In this study, we investigated the conformational heterogeneity of a G-rich seq...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/24/10/1988 |