LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

Abstract Background The abnormal expression of non-coding RNAs (ncRNAs), such as microRNAs and long ncRNAs, often contribute to the development of cancers. miR-200c functions as a tumour suppressor that impacts the growth of bladder cancer cells and the epithelial-to-mesenchymal transition (EMT). Ln...

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Bibliographic Details
Main Authors: Ran Xu, Xuan Zhu, Fangzhi Chen, Changkun Huang, Kai Ai, Hongtao Wu, Lei Zhang, Xiaokun Zhao
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Cancer Cell International
Subjects:
LncRNA
XIST
MiR-200c
Bladder cancer
Stem cell-like cells
EMT
Online Access:http://link.springer.com/article/10.1186/s12935-018-0540-0

Internet

http://link.springer.com/article/10.1186/s12935-018-0540-0

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