Time to relapse in chronic lymphocytic leukemia and DNA-methylation-based biological age

Abstract Chronic lymphocytic leukemia (CLL) is a mature B cell neoplasm with a predilection for older individuals. While previous studies have identified epigenetic signatures associated with CLL, whether age-related DNA methylation changes modulate CLL relapse remains elusive. In this study, we exa...

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Bibliographic Details
Main Authors: Drew R. Nannini, Rene Cortese, Peter Egwom, Senthilnathan Palaniyandi, Gerhard C. Hildebrandt
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Clinical Epigenetics
Subjects:
Online Access:https://doi.org/10.1186/s13148-023-01496-8