Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home

Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home

Abstract Background Older people achieve lower levels of antibody titers than younger populations after Covid-19 vaccination and show a marked waning humoral immunity over time, likely due to the senescence of the immune system. Nevertheless, age-related predictive factors of the waning humoral immu...

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Bibliographic Details
Main Authors: María del Mar Pozo-Balado, Ángel Bulnes-Ramos, Israel Olivas-Martínez, Vanesa Garrido-Rodríguez, Carmen Lozano, Ana I. Álvarez-Ríos, Berta Sánchez-Sánchez, Encarnación Sánchez-Bejarano, Isabel Maldonado-Calzado, José Manuel Martín-Lara, Juan Antonio Santamaría, Rafael Bernal, María Francisca González-Escribano, Manuel Leal, Yolanda M. Pacheco
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Immunity & Ageing
Subjects:
BNT162b2 vaccine
Magnitude and persistence of humoral response
Antibody waning
Nursing home
Thymic-function
Sj/β-TRECs ratio
Online Access:https://doi.org/10.1186/s12979-023-00334-y

Internet

https://doi.org/10.1186/s12979-023-00334-y

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