Combined Cerebrospinal Fluid Neurofilament Light Chain Protein and Chitinase-3 Like-1 Levels in Defining Disease Course and Prognosis in Multiple Sclerosis

Combined Cerebrospinal Fluid Neurofilament Light Chain Protein and Chitinase-3 Like-1 Levels in Defining Disease Course and Prognosis in Multiple Sclerosis

Background: Neurofilament light chain protein (NFL) and chitinase3-like1 (CHI3L1) have gained importance recently as prognostic biomarkers in multiple sclerosis (MS).Objectives: We aimed to investigate NFL and CHI3L1 cerebrospinal fluid (CSF) profiles in multiple sclerosis and the informative and pr...

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Bibliographic Details
Main Authors: Sara Gil-Perotin, Jessica Castillo-Villalba, Laura Cubas-Nuñez, Raquel Gasque, David Hervas, Josep Gomez-Mateu, Carmen Alcala, Francisco Perez-Miralles, Francisco Gascon, Jose Andres Dominguez, Bonaventura Casanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neurology
Subjects:
YKL-40
CHI3L1
NFL
progressive multiple sclerosis
gadolinium-enhancing lesions
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01008/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01008/full

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