Cordycepin Inhibits Growth and Metastasis Formation of MDA-MB-231 Xenografts in Nude Mice by Modulating the Hedgehog Pathway

Cordycepin Inhibits Growth and Metastasis Formation of MDA-MB-231 Xenografts in Nude Mice by Modulating the Hedgehog Pathway

We previously found that cordycepin inhibits the growth and metastasis formation of MDA-MB-231 cells through the Hedgehog pathway but has not validated this in vivo. In this study, we confirmed cordycepin’s anti-triple-negative breast cancer (TNBC) effect in nude mice and documented its mechanism. W...

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Bibliographic Details
Main Authors: Wenya Wu, Xiaomin Li, Meng Qi, Xin Hu, Fenghua Cao, Xiaoping Wu, Junsheng Fu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Cordyceps militaris</i>
cordycepin
triple-negative breast cancer
Hedgehog pathway
Online Access:https://www.mdpi.com/1422-0067/23/18/10362

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https://www.mdpi.com/1422-0067/23/18/10362

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