Natural functional SNPs in miR-155 alter its expression level, blood cell counts and immune responses

Natural functional SNPs in miR-155 alter its expression level, blood cell counts and immune responses

miR-155 has been confirmed to be a key factor in immune responses in humans and other mammals. Therefore, investigation of variations in miR-155 could be useful for understanding the differences in immunity between individuals. In this study, four SNPs in miR-155 were identified in mice (Mus musculu...

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Bibliographic Details
Main Authors: Congcong Li, Huabin He, An Liu, Huazhen Liu, Haibo Huang, Changzhi Zhao, Lu Jing, Juan Ni, Lilin Yin, Suqin Hu, Hui Wu, Xinyun Li, Shu-Hong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Immunology
Subjects:
immune response
expression level
miR-155
Blood parameters
natural functional mutation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00295/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00295/full

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