Synthesis and Antimicrobial Activity Screening of Piperazines Bearing <i>N</i>,<i>N′</i>-Bis(1,3,4-thiadiazole) Moiety as Probable Enoyl-ACP Reductase Inhibitors

Synthesis and Antimicrobial Activity Screening of Piperazines Bearing <i>N</i>,<i>N′</i>-Bis(1,3,4-thiadiazole) Moiety as Probable Enoyl-ACP Reductase Inhibitors

A new <i>N</i>,<i>N′</i>-disubstituted piperazine conjugated with 1,3,4-thiadiazole and 1,2,4-triazole was prepared and the chemical structures were identified by IR, NMR and elemental analysis. All the prepared compounds were tested for their antimicrobial activity. The anti...

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Bibliographic Details
Main Authors: Alaa Z. Omar, Najla A. Alshaye, Tawfik M. Mosa, Samir K. El-Sadany, Ezzat A. Hamed, Mohamed A. El-Atawy
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
enoyl reductase
MOE
1,3,4-thiadiazole
piperazine
1,2,4-triazole
Online Access:https://www.mdpi.com/1420-3049/27/12/3698

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https://www.mdpi.com/1420-3049/27/12/3698

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