Safety and efficacy of placental mesenchymal stem cell-derived extracellular vesicle in severe COVID-19 patients: Phase I & II Clinical Trials

Safety and efficacy of placental mesenchymal stem cell-derived extracellular vesicle in severe COVID-19 patients: Phase I & II Clinical Trials

Introduction: Most mortality in COVID-19 cases was due to the increased inflammatory cytokines and cytokine storm. As mesenchymal stem cells (MSCs) possess immunomodulatory properties, this study assessed the therapeutic effects of placental MSC-derived extracellular vesicles on the inflammation and...

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Main Authors: Mehdi Jahedi Zargar, Saeed Heidari Keshel, Saeid Kaviani, Mohammad Zahraei, Azadeh Izadyari Aghmiuni, Ali Amir Savadkoohi, Hamidreza Jamaati, Mohammad Samet, Mahsa Soufizomorrod, Mina Soufi Zomorrod, Faeze Sadat Heidari, Mohamad Reza Mirjalili, Payam Tabarsi, Mohammadreza Soroush, Rasoul Aliannejad, Mojtaba Javani, Hosein Shafiii, Mohammad Vasei, Masoud Soleimani
Format: Article
Language:English
Published: Negah Institute for Scientific Communication 2022-08-01
Series:Anatomical Sciences Journal
Subjects:
covid‐19
extracellular vesicles
mesenchymal stromal cell
placenta-derived mesenchymal stem cell
acute respiratory distress syndrome
Online Access:http://anatomyjournal.ir/article-1-585-en.pdf

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http://anatomyjournal.ir/article-1-585-en.pdf

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