Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

Background: Free fatty acid-induced lipotoxicity is considered to play an important role in pancreatic β-cell dysfunction. The effect of ginsenosides on palmitic acid-induced pancreatic beta-cells cell death and failure of glucose-stimulated secretion of insulin (GSIS) was evaluated in this study. M...

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Bibliographic Details
Main Authors: Dahae Lee, Sungyoul Choi, Ki Sung Kang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Ginseng Research
Subjects:
ginsenosides
protopanaxadiol
palmitic acid
lipotoxicity
apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845323000210

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http://www.sciencedirect.com/science/article/pii/S1226845323000210

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