Spermiogenesis alterations in the absence of CTCF revealed by single cell RNA sequencing

CTCF is an architectonic protein that organizes the genome inside the nucleus in almost all eukaryotic cells. There is evidence that CTCF plays a critical role during spermatogenesis as its depletion produces abnormal sperm and infertility. However, defects produced by its depletion throughout sperm...

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Bibliographic Details
Main Authors: Ulises Torres-Flores, Fernanda Díaz-Espinosa, Tayde López-Santaella, Rosa Rebollar-Vega, Aarón Vázquez-Jiménez, Ian J. Taylor, Rosario Ortiz-Hernández, Olga M. Echeverría, Gerardo H. Vázquez-Nin, María Concepción Gutierrez-Ruiz, Inti Alberto De la Rosa-Velázquez, Osbaldo Resendis-Antonio, Abrahan Hernández-Hernandez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1119514/full