Protocol for comparing gene-level selection on coding mutations between two groups of samples with Coselens

Summary: The study of genes that evolve under conditional selection can shed light on the genomic underpinnings of adaptation, revealing epistasis and phenotypic plasticity. This protocol describes how to use the Coselens package to compare gene-level selection between two groups of samples. After i...

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Bibliographic Details
Main Authors: Jaime Iranzo, George Gruenhagen, Jorge Calle-Espinosa, Eugene V. Koonin
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723000758