C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita

C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita

IntroductionInflammatory epidermolysis bullosa acquisita (EBA) is characterized by a neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the development of skin inflammation and blistering. The antibody transfer model of EBA closely mirrors this EBA phenotype.MethodsTo bet...

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Bibliographic Details
Main Authors: Christian F. Guerrero-Juarez, Paul Schilf, Jing Li, Maria Paula Zappia, Lei Bao, Payal M. Patel, Jenny Gieseler-Tillmann, Sripriya Murthy, Connor Cole, Maria Sverdlov, Maxim V. Frolov, Takashi Hashimoto, Norito Ishii, Thomas Rülicke, Katja Bieber, Ralf J. Ludwig, Christian D. Sadik, Kyle T. Amber
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
epidermolysis bullosa acquisita
pemphigoid
neutrophil
single cell RNA seq
C-type lectin receptor (CLRs)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1266359/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1266359/full

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