Hydrolytic Stability of New Amino Acids Analogues of Memantine

Hydrolytic Stability of New Amino Acids Analogues of Memantine

In the present work, the hydrolytic stability of new memantine analogues modified with amino acids, at different pH corresponding to the human biological liquids and organs, was evaluated. Memantine is an uncompetitive N-methyl-<span style="font-variant: small-caps;">d</span>-a...

Full description

Bibliographic Details
Main Authors: Aleksandra Tencheva, Radoslav Chayrov, Petko Mandjukov, Dancho Danalev, Ivanka Stankova
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Scientia Pharmaceutica
Subjects:
amino acids
memantine
hydrolytic stability
prodrug
physiological pH
non-linear calibration
Online Access:https://www.mdpi.com/2218-0532/88/3/38

Internet

https://www.mdpi.com/2218-0532/88/3/38

Similar Items