A combined administration of GABA agonist and L-histidine synergistically alleviates obesity-induced neuro-lipotoxicity and distorted metabolic transcriptome

A combined administration of GABA agonist and L-histidine synergistically alleviates obesity-induced neuro-lipotoxicity and distorted metabolic transcriptome

Obesity stands as a pervasive and significant global health issue, with a lack of definitive and curative therapeutic solutions currently available. Here we studied the synergetic ameliorating effect of coupled administration of GABA agonist; baclofen with histidine against the high fat (HFD) induce...

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Bibliographic Details
Main Authors: Esam S. Al-Malki, Omar A. Ahmed-Farid, Mahmoud M.A. Moustafa, Shimaa A. Haredy, Omnia A. Badr, Nesreen Nabil Omar, Robert J. Linhardt, Mohamad Warda
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Scientific African
Subjects:
L-histidine
Fluoxetine
GABA agonist
Gene expression
Obesity
Rats
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227624001224

Internet

http://www.sciencedirect.com/science/article/pii/S2468227624001224

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