The mitochondrial transcription machinery genes are upregulated in acute myeloid leukemia and associated with poor clinical outcome
Background: Acute myeloid leukemia (AML) is characterized by rapid growth of abnormal blasts that overcrowd normal hematopoiesis. Defective mitochondrial biogenesis has been implicated in AML, which we believe is partly due to the deregulation of the mitochondrial transcription machinery (MTM) genes...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-06-01
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| Series: | Metabolism Open |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258993681930009X |