The effect of TEMPOL pretreatment on postoperative cognitive function, inflammatory response, and oxidative stress in aged rats under sevoflurane anesthesia

The effect of TEMPOL pretreatment on postoperative cognitive function, inflammatory response, and oxidative stress in aged rats under sevoflurane anesthesia

Abstract Introduction The heterocyclic compound 4‐hydroxy‐(2,2,6,6‐Tetramethylpiperidin‐1‐yl)oxyl (TEMPOL) has a protective effect on neurological function in brain tissues damaged by ischemia and hypoxia. This study explored the effects of TEMPOL pretreatment on postoperative cognitive function in...

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Bibliographic Details
Main Authors: Tianpin Liu, Tianzi Chen, Jianhua Gong, Changchang You, Bo Zhang, Caiyun Luo, Zhigui Liu, Chun Chen
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Immunity, Inflammation and Disease
Subjects:
aged rats
cognitive function
inflammatory response
oxidative stress
sevoflurane anesthesia
TEMPOL pretreatment
Online Access:https://doi.org/10.1002/iid3.1023

Internet

https://doi.org/10.1002/iid3.1023

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