Hylan G-F20 and galactomannan joint flares are associated to acute synovitis and release of inflammatory cytokines

Hylan G-F20 and galactomannan joint flares are associated to acute synovitis and release of inflammatory cytokines

Abstract Background Injection of Hylan G-F20 (HY) into joints may provoke local flares, which mechanisms may involve reaction to protein contaminants. We have previously developed a protein-free saline-soluble galactomannan derived from guar gum (GM) that displays both analgesia and chondroprotectio...

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Bibliographic Details
Main Authors: Rodolfo de Melo Nunes, Pablyana Leila Rodrigues Cunha, Ana Carolina Matias Dinelly Pinto, Virgínia Claudia Carneiro Girão, Judith Pessoa de Andrade Feitosa, Francisco Airton Castro Rocha
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Advances in Rheumatology
Subjects:
Galactomannans
Hyaluronic acid
Hylan G-F20
Osteoarthritis
Polysaccharides
Viscosupplementation
Online Access:http://link.springer.com/article/10.1186/s42358-020-00127-7

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http://link.springer.com/article/10.1186/s42358-020-00127-7

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