The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations.

The characterization of immortalized canine osteosarcoma (OS) cell lines used for research has historically been based on phenotypic features such as cellular morphology and expression of bone specific markers. With the increasing use of these cell lines to investigate novel therapeutic approaches p...

Full description

Bibliographic Details
Main Authors: Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K Karlsson, Cheryl A London, Heather L Gardner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0274383