Anticancer properties and mechanism of action of the fungal nucleoside clitocine and its derivatives

Clitocine (CLT) is an atypical nitro-containing pyrimidine nucleoside bearing a ribofuranosyl moiety attached to the exocyclic 4-amino position. It has been isolated first from the fungus Clitocybe inversa and then from fruiting bodies of Leucopaxillus giganteus. Two intramolecular hydrogen-bonds be...

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Bibliographic Details
Main Author: Christian Bailly
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417423000237