Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome

The concept of the pre-cancerous niche applies the ‘seed and soil’ theory of metastasis to the initial process of carcinogenesis. TP53 is at the nexus of this process and, in the context of Li-Fraumeni Syndrome (LFS), is a key determinant of the conditions in which cancers are formed and progress. I...

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Bibliographic Details
Main Authors: Pan Pantziarka, Sarah Blagden
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/7/1621