Genetic Analysis of Primaquine Tolerance in a Patient with Relapsing Vivax Malaria

Genetic Analysis of Primaquine Tolerance in a Patient with Relapsing Vivax Malaria

Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide varia...

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Detalhes bibliográficos
Main Authors: A. Taylor Bright, Thamer Alenazi, Sandra Shokoples, Joel Tarning, Giacomo M. Paganotti, Nicholas J. White, Stanley Houston, Elizabeth A. Winzeler, Stephanie K. Yanow
Formato: Artigo
Idioma:English
Publicado em: Centers for Disease Control and Prevention 2013-05-01
Colecção:Emerging Infectious Diseases
Assuntos:
malaria
Plasmodium vivax
primaquine
relapse
genetics
parasites
Acesso em linha:https://wwwnc.cdc.gov/eid/article/19/5/12-1852_article

Internet

https://wwwnc.cdc.gov/eid/article/19/5/12-1852_article

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