Genetic Analysis of Primaquine Tolerance in a Patient with Relapsing Vivax Malaria

Genetic Analysis of Primaquine Tolerance in a Patient with Relapsing Vivax Malaria

Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide varia...

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Bibliographic Details
Main Authors: A. Taylor Bright, Thamer Alenazi, Sandra Shokoples, Joel Tarning, Giacomo M. Paganotti, Nicholas J. White, Stanley Houston, Elizabeth A. Winzeler, Stephanie K. Yanow
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-05-01
Series:Emerging Infectious Diseases
Subjects:
malaria
Plasmodium vivax
primaquine
relapse
genetics
parasites
Online Access:https://wwwnc.cdc.gov/eid/article/19/5/12-1852_article

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