Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Summary: Various populations of cancer stem cells (CSCs) have been identified in hepatocellular carcinoma (HCC). Wnt signaling is variably activated in HCC and regulates CSCs and tumorigenesis. We explored cell-to-cell Wnt and stemness heterogeneity in HCC by labeling freshly isolated cancer cells w...

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Bibliographic Details
Main Authors: Wen-Ying Liao, Chung-Chi Hsu, Tze-Sian Chan, Chia-Jui Yen, Wei-Yu Chen, Hung-Wei Pan, Kelvin K. Tsai
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367112030059X

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http://www.sciencedirect.com/science/article/pii/S221367112030059X

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