Effects of risperidone/paliperidone versus placebo on cognitive functioning over the first 6 months of treatment for psychotic disorder: secondary analysis of a triple-blind randomised clinical trial

Abstract The drivers of cognitive change following first-episode psychosis remain poorly understood. Evidence regarding the role of antipsychotic medication is primarily based on naturalistic studies or clinical trials without a placebo arm, making it difficult to disentangle illness from medication...

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Bibliographic Details
Main Authors: Kelly Allott, Hok Pan Yuen, Lara Baldwin, Brian O’Donoghue, Alex Fornito, Sidhant Chopra, Barnaby Nelson, Jessica Graham, Melissa J. Kerr, Tina-Marie Proffitt, Aswin Ratheesh, Mario Alvarez-Jimenez, Susy Harrigan, Ellie Brown, Andrew D. Thompson, Christos Pantelis, Michael Berk, Patrick D. McGorry, Shona M. Francey, Stephen J. Wood
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02501-7