Unique CLR expression patterns on circulating and tumor-infiltrating DC subsets correlated with clinical outcome in melanoma patients

Unique CLR expression patterns on circulating and tumor-infiltrating DC subsets correlated with clinical outcome in melanoma patients

Subversion of immunity by tumors is a crucial step for their development. Dendritic cells (DCs) are strategic immune cells that orchestrate anti-tumor immune responses but display altered functions in cancer. The bases for such DCs’ hijacking are not fully understood. Tumor cells harbor unusual glyc...

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Bibliographic Details
Main Authors: Eleonora Sosa Cuevas, Jenny Valladeau-Guilemond, Stephane Mouret, Benoît Roubinet, Florence de Fraipont, Ludovic Landemarre, Julie Charles, Nathalie Bendriss-Vermare, Laurence Chaperot, Caroline Aspord
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
CLR
human DC subsets
melanoma
immune subversion
glycan
cDC1s
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040600/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040600/full

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