The role of cGAS-STING signaling in rheumatoid arthritis: from pathogenesis to therapeutic targets
Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily characterized by erosive and symmetric polyarthritis. As a pivotal axis in the regulation of type I interferon (IFN-I) and innate immunity, the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway h...
| Hauptverfasser: | , |
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| Format: | Artikel |
| Sprache: | English |
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Frontiers Media S.A.
2024-09-01
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| Schriftenreihe: | Frontiers in Immunology |
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| Online Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1466023/full |