Caffeoyl-Prolyl-Histidine Amide Inhibits Fyn and Alleviates Atopic Dermatitis-Like Phenotypes via Suppression of NF-κB Activation

Caffeoyl-Prolyl-Histidine Amide Inhibits Fyn and Alleviates Atopic Dermatitis-Like Phenotypes via Suppression of NF-κB Activation

Caffeic acid (CA) is produced from a variety of plants and has diverse biological functions, including anti-inflammation activity. It has been recently demonstrated that caffeoyl-prolyl-histidine amide (CA-PH), which is CA conjugated with proline-histidine dipeptide, relieves atopic dermatitis (AD)-...

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Bibliographic Details
Main Authors: Hayan Jeong, Jee Youn Shin, Kwanghyun Lee, Su-Jin Lee, Hyo-Jin Chong, Hyeri Jeong, Young-Eun Jeon, Dong-Sik Shin, Sunhyae Jang, Kyu Han Kim, Seok-In Kim, Yoon-Sik Lee, Bong-Gun Ju
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
atopic dermatitis
CA-PH
Fyn
NF-κB
SYK
skin atrophy
Online Access:https://www.mdpi.com/1422-0067/21/19/7160

Internet

https://www.mdpi.com/1422-0067/21/19/7160

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