Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality

Drug-metabolizing enzymes (DMEs) and transporters play a major role in drug efficacy and safety. They are regulated at multiple levels and by multiple factors. Estimating their expression and activity could contribute to predicting drug pharmacokinetics and their regulation by drugs or pathophysiolo...

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Bibliographic Details
Main Authors: Anna Gagliardi, Gzona Bajraktari-Sylejmani, Elisabetta Barocelli, Johanna Weiss, Juan Pablo Rigalli
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/8/1745