Combined burden and functional impact tests for cancer driver discovery using DriverPower

Combined burden and functional impact tests for cancer driver discovery using DriverPower

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer who...

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Bibliographic Details
Main Authors: Shimin Shuai, PCAWG Drivers and Functional Interpretation Working Group, Steven Gallinger, Lincoln Stein, PCAWG Consortium
Format: Article
Language:English
Published: Nature Portfolio 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13929-1

Internet

https://doi.org/10.1038/s41467-019-13929-1

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