Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation.

Host control of influenza A virus (IAV) is associated with exuberant pulmonary inflammation characterized by the influx of myeloid cells and production of proinflammatory cytokines including interferons (IFNs). It is unclear, however, how the immune system clears the virus without causing lethal imm...

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Bibliographic Details
Main Authors: Sebastian A Stifter, Nayan Bhattacharyya, Roman Pillay, Manuela Flórido, James A Triccas, Warwick J Britton, Carl G Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4701664?pdf=render