circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells

Oxidized low-density lipoprotein (ox-LDL) is a significant risk factor for various brain vascular diseases. Circular RNA (circRNA) is involved in the pathogenesis of brain vascular diseases. This study revealed the roles of circ_CHFR in ox-LDL-mediated cell proliferation, apoptosis, and endothelial-...

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Bibliographic Details
Main Authors: Wu Shanwu, Yang Sheng, Qu Hongyan
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2021-0082