Impact of time to antibiotics on clinical outcome in paediatric febrile neutropenia: a target trial emulation of 1685 episodesResearch in context

Impact of time to antibiotics on clinical outcome in paediatric febrile neutropenia: a target trial emulation of 1685 episodesResearch in context

Summary: Background: Prompt antibiotic administration for febrile neutropenia (FN) is standard of care, and targets of time to antibiotics (TTA) <60 min are common. We sought to determine the effect of TTA ≥60 versus <60 min on adverse outcomes (intensive care unit (ICU) admission or death) i...

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Main Authors: Gabrielle M. Haeusler, S Ghazaleh Dashti, Fiona James, Franz E. Babl, Meredith L. Borland, Julia E. Clark, Bhavna Padhye, Heather Tapp, Frank Alvaro, Trisha Soosay Raj, Thomas Walwyn, David S. Ziegler, Leanne Super, Lisa Hall, Daniel K. Yeoh, Coen Butters, Brendan McMullan, Diane M.T. Hanna, Richard De Abreu Lourenco, Monica A. Slavin, Bob Phillips, Karin A. Thursky
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:The Lancet Regional Health. Western Pacific
Subjects:
Febrile neutropenia (FN)
Time to antibiotics (TTA)
Children with cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2666606524002207

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http://www.sciencedirect.com/science/article/pii/S2666606524002207

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