Osteoprotective Effects in Postmenopausal Osteoporosis Rat Model: Oral Tocotrienol vs. Intraosseous Injection of Tocotrienol-Poly Lactic-Co-Glycolic Acid Combination

Osteoprotective Effects in Postmenopausal Osteoporosis Rat Model: Oral Tocotrienol vs. Intraosseous Injection of Tocotrienol-Poly Lactic-Co-Glycolic Acid Combination

Osteoporosis, the most common bone disease, is associated with compromised bone strength and increased risk of fracture. Previous studies have shown that oxidative stress contributes to the progression of osteoporosis. Specifically, for postmenopausal osteoporosis, the reduction in estrogen levels l...

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Bibliographic Details
Main Authors: Nurul ‘Izzah Ibrahim, Hasnul ‘Iffah Mohd Noor, Ahmad Naqib Shuid, Sharlina Mohamad, Mohd Maaruf Abdul Malik, Putri Ayu Jayusman, Ahmad Nazrun Shuid, Isa Naina Mohamed
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
osteoporosis
oxidative stress
tocotrienol
PLGA
intraosseous
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.706747/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.706747/full

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