HOXB5 cooperates with NKX2-1 in the transcription of human RET.

The enteric nervous system (ENS) regulates peristaltic movement of the gut, and abnormal ENS causes Hirschsprung's disease (HSCR) in newborns. HSCR is a congenital complex genetic disorder characterised by a lack of enteric ganglia along a variable length of the intestine. The receptor tyrosine...

Full description

Bibliographic Details
Main Authors: Jiang Zhu, Maria-Mercedes Garcia-Barcelo, Paul Kwong Hang Tam, Vincent Chi Hang Lui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108997?pdf=render