Discovery of Natural Small Molecules Promoting Collagen Secretion by High-Throughput Screening in <i>Caenorhabditis elegans</i>

Discovery of Natural Small Molecules Promoting Collagen Secretion by High-Throughput Screening in <i>Caenorhabditis elegans</i>

Advancing approaches for drug screening are in great demand to explore natural small molecules that may play important roles in collagen biogenesis, secretion, and assembly, which may find novel lead compounds for treating collagen-related diseases or preventing skin aging. In this study, we generat...

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Bibliographic Details
Main Authors: Jinyang Fang, Xinyue Wu, Xi’nan Meng, Dejin Xun, Suhong Xu, Yi Wang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
high throughput drug screening
collagen synthesis and secretion
natural small molecule
COL-12
<i>C. elegans</i>
transfer learning
Online Access:https://www.mdpi.com/1420-3049/27/23/8361

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https://www.mdpi.com/1420-3049/27/23/8361

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