The lncRNA RMST is drastically downregulated in anaplastic thyroid carcinomas where exerts a tumor suppressor activity impairing epithelial-mesenchymal transition and stemness

Abstract Thyroid cancer is the most prevalent endocrine malignancy and comprises a wide range of lesions subdivided into differentiated (DTC) and undifferentiated thyroid cancer (UTC), mainly represented by the anaplastic thyroid carcinoma (ATC). This is one of the most lethal malignancies in humank...

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Bibliographic Details
Main Authors: Marco De Martino, Simona Pellecchia, Francesco Esposito, Federica Liotti, Sara Carmela Credendino, Nella Prevete, Myriam Decaussin-Petrucci, Paolo Chieffi, Gabriella De Vita, Rosa Marina Melillo, Alfredo Fusco, Pierlorenzo Pallante
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01514-x