Nuclear and Mitochondrial Circulating Cell-Free DNA Is Increased in Patients With Inflammatory Bowel Disease in Clinical Remission

Nuclear and Mitochondrial Circulating Cell-Free DNA Is Increased in Patients With Inflammatory Bowel Disease in Clinical Remission

Background: The role of cell-free DNA (cfDNA) in the pathogenesis of inflammatory bowel disease (IBD) has been recently suggested. The aim of this study was to analyze circulating cfDNA and deoxyribonuclease (DNase) activity in IBD patients in clinical remission.Materials and Methods: Plasma and ser...

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Bibliographic Details
Main Authors: Zuzana Vrablicova, Kristina Tomova, Lubomira Tothova, Janka Babickova, Barbora Gromova, Barbora Konecna, Robert Liptak, Tibor Hlavaty, Roman Gardlik
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Medicine
Subjects:
extracellular DNA
deoxyribonuclease (DNase)
remission
Crohn's disease
ulcerative colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.593316/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.593316/full

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