Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome
ABSTRACT Damaged DNA typically imposes stringent controls on eukaryotic cell cycle progression, ensuring faithful transmission of genetic material. Some DNA breaks, and the resulting rearrangements, are advantageous, however. For example, antigenic variation in the parasitic African trypanosome, Try...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-08-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01252-19 |