Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome

Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome

ABSTRACT Damaged DNA typically imposes stringent controls on eukaryotic cell cycle progression, ensuring faithful transmission of genetic material. Some DNA breaks, and the resulting rearrangements, are advantageous, however. For example, antigenic variation in the parasitic African trypanosome, Try...

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Bibliographic Details
Main Authors: Lucy Glover, Catarina A. Marques, Olga Suska, David Horn
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
RPA2
damage response
telomere
Online Access:https://journals.asm.org/doi/10.1128/mBio.01252-19

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