Transcriptome and Regulatory Network Analyses of CD19-CAR-T Immunotherapy for B-ALL

Transcriptome and Regulatory Network Analyses of CD19-CAR-T Immunotherapy for B-ALL

Chimeric antigen receptor (CAR) T cell therapy has exhibited dramatic anti-tumor efficacy in clinical trials. In this study, we reported the transcriptome profiles of bone marrow cells in four B cell acute lymphoblastic leukemia (B-ALL) patients before and after CD19-specific CAR-T therapy. CD19-CAR...

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Bibliographic Details
Main Authors: Qiong Zhang, Hui Hu, Si-Yi Chen, Chun-Jie Liu, Fei-Fei Hu, Jianming Yu, Yaohui Wu, An-Yuan Guo
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Genomics, Proteomics & Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022919300932

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http://www.sciencedirect.com/science/article/pii/S1672022919300932

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