Association of Tumor Hydroxyindole O-Methyltransferase and Serum 5-Methoxytryptophan with Long-Term Survival of Hepatocellular Carcinoma

Association of Tumor Hydroxyindole O-Methyltransferase and Serum 5-Methoxytryptophan with Long-Term Survival of Hepatocellular Carcinoma

5-methoxytryptophan (5-MTP) is a recently discovered tryptophan (Trp) metabolite with anti-inflammatory and tumor-suppressing actions. Its synthesis is catalyzed by hydroxyindole O-methyltransferase (HIOMT). HIOMT levels were reported to be decreased in some patients with colorectal, pancreatic and...

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Bibliographic Details
Main Authors: Bor-Sheng Ko, Shu-Man Liang, Tzu-Ching Chang, Jing-Yiing Wu, Po-Hsun Lee, Yu-Juei Hsu, Cheng-Chin Kuo, Jun-Yang Liou, Kenneth K. Wu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
hepatocellular carcinoma
5-methoxytryptophan
hydroxyindole O-methyltransferase
kynurenine
biomarker
Online Access:https://www.mdpi.com/2072-6694/13/21/5311

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https://www.mdpi.com/2072-6694/13/21/5311

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